Billy tvinges til at gå til boksning af sin far, selvom han er en elendig slagsbror. En dag, da den arme dreng er til træning, ser han, at de i lokalet ved siden af danser ballet. Billy lader sig overtale til at deltage af balletlærerindens datter. Da Billys far opdager sønnens "umandige" interesse, bliver han rasende, og Billy bliver korporligt fjernet fra øvelokalet. Men lærerinden, der har set Billys talent, giver ikke op.
Tom og Kate Baker er forældre til ikke færre end 12 børn i alle aldre. Da Tom får tilbudt et nyt job i en anden by, må hele familien pakke flyttekasserne. Børnene er dog ikke glade for at skulle flytte væk fra venner og kærester. Samtidig tager Kate på turne for at gøre reklame for sin nye bog, og pludselig må Tom både håndtere et krævende nyt job og en ikke mindre krævende børneflok.
Candice, en 12-årig pige, har mistet sin lillesøster og forsøger at bringe glæden tilbage i sin sorgplagede familie. Intet er som før siden hendes søsters død og hendes mors depression. Men i skolen får hun en ny veninde.
Leo is an ordinary teenager who has moved into a high-tech "smart'' house with his mother, inventor stepfather and Eddy, the computer that runs the house. Leo's life becomes less ordinary when, one day, he discovers a secret underground lab that houses three experiments: superhuman teenagers. The trio -- Adam, the strong one, Bree, the fast one and Chase, the smart one -- convinces Leo and his parents to let them leave their lab and join Leo at school, where they try to fit in while having to manage their unpredictable bionic strengths. As Leo figures out a way to keep his new pals' bionic abilities a secret, they help him build self-confidence.
K.C. Cooper, a high school math whiz and karate black-belt, learns that her parents are spies when they recruit her to join them in the secret government agency, The Organization. While she now has the latest spy gadgets at her disposal, K.C. has a lot to learn about being a spy, including keeping her new gig a secret from her best friend Marisa. Together, K.C. and her parents, Craig and Kira, and her younger siblings, Ernie and Judy (a humanoid robot), try to balance everyday family life while on undercover missions, near and far, to save the world.
