Den storslåede afslutning på den ukendte historie om heksene i Oz begynder. Elphaba, der er dæmoniseret som Den Onde Heks fra Vest, lever i eksil og kæmper for sandheden. Glinda, symbolet på godhed, regerer i Smaragdbyen. Men da en pige fra Kansas ankommer, sættes skæbnen i gang. De to må genforenes, konfrontere deres fortid og virkelig se hinanden for at forandre sig selv og Oz til det bedre.
In the year 2138, virtual reality gaming is booming. Yggdrasil, a popular online game is quietly shut down one day. However, one player named Momonga decides to not log out. Momonga is then transformed into the image of a skeleton as "the most powerful wizard." The world continues to change, with non-player characters (NPCs) beginning to feel emotion. Having no parents, friends, or place in society, this ordinary young man Momonga then strives to take over the new world the game has become.
