50年続いた大戦に勝利した大亜細亜聯邦共和國。ところが、その繁栄の裏側では様々な病気が人類を脅かしていた。そんな中、重い病に苦しむ妻・ミドリの為に、人間のあらゆる部位を自在に造り出す“新造細胞”理論を提唱していた東博士は、軍部の援助により本格的に研究を開始するが、実験場から新生命体“新造人間”が誕生。大多数は軍によって始末されるも、生き延びたブライキング・ボスら数名の新造人間たちは、生きる為に容易に戦いの道を選んでしまう人類の世界を破壊しようと、攻撃を仕掛けて来た。再びの戦火。それを収めるべく立ち上がったのは、先の大戦で戦死し、新造細胞によって蘇生した東博士の息子・鉄也だった。
“Z”との戦いの末、ガッチャマンらヒーローたちはそれぞれの世界へ帰還した。だが程なく、平穏な日々を送る笑（エミ）の前に「力を貸してほしい」と再びガッチャマン＝健が現われる。2人が降り立ったのは、健の世界とはまた別の“科学忍者隊”が存在するパラレルワールド。2人はそこでテッカマン、ポリマー、キャシャーンと合流するが、再会を喜ぶ間もなく、彼らの前に敵となった科学忍者隊の創設者・南部博士が立ちはだかる。
After the murder of Luna, the robot society that rules the planet starts to rust and decay. Death and despair spread through the land like wildfire. The only one unaffected by the affliction that becomes known as "The Ruin" is Luna's assassin, Casshern. Unable to remember if he really triggered this capital sin against the entire mechanized civilization, Casshern embarks on a journey to unravel the mystery that connects him, Luna, and the plague.
Dr. Azuma creates robots to benefit mankind, but they unexpectedly rebel and begin to destroy everything in their paths. To deal with the catastrophe, Dr. Azuma's son volunteers to become a human robot, even though he knows he will never be able to return to human form again. He confronts this grave situation to ensure a bright future for all humans.
Emi is a seventeen-year-old girl living in Shibuya. Her father is always away with work and she's grown listless. Suddenly, a twist of fate involving a certain magical item changes everything. A mysterious pencil, of all things, is linked to the appearance of heroes from another world! Could this be the start to the excitement she's so desperately craving, or is there something more?
The villainous casts of the original Time-Bokan series compete to win the right to appear in this program, daring to employ all their mean, make-shift and frivolous tricks. The winners get to display their idiotic, yet appealing performances in the mystic Tatsunokon Kingdom program.
Far in the future, ecological disaster on Earth led humans to create a race of androids called Neoroids to clean up the mess but they promptly turned on their human masters and enslaved them. Enter a lone fighter named Casshan with a mission to free humanity ... and restore his family's honor.
