Šoreiz Ītenam Hantam piedāvā kārtējo "neiespējamo" misiju – atgūt trīs plutonija bumbas, kas ir nozagtas krieviem. Pēc tam, kad Ītena Hanta un viņa IMF komandas jaunais uzdevums cieš pilnīgu fiasko, viņam kopā ar komandas biedriem un citiem sabiedrotajiem ir jādara viss, lai labotu kāda pagātnē pieņemta nepareiza lēmuma tālejošās sekas.
Kad NMS izformē un Ītans Hants vairs nav ierastajā darbā, viņa komanda negaidīti sastopas ar sazarotu starptautisku augsta līmeņa profesionālu specaģentu tīklu - Sindikātu. Šī "slepenā nācija" ir pārņemta ar ideju par jaunas pasaules kārtības ieviešanu un plāno postošu terora aktu sēriju. Ītans un viņa kompānija apvienojas ar diskreditētu britu aģenti Ilzu Faustu un ķeras pie savas visneieespējamākās misijas...
Viņas Majestātes Slepenā dienesta visefektīvākā aģente Lorēna Brotone ir vienlīdz izsmalcināta un diskrēta informācijas iegūšanā kā arī nāvējoša pretējās nometnes spiegiem, gatava uz pilnīgi visu, lai paveiktu sev doto uzdevumu un paliktu dzīva. Nosūtīta uz Berlīni īsi pirms mūra krišanas, lai atgūtu dosjē ar nopludinātiem spiegu vārdiem, viņa nokļūst brutālā lielvaru savstarpējā cīņā par Berlīnes, Vācijas un visas Eiropas nākotni.
The Lupin Collection, a vast ensemble of dangerous items acquired by the legendary gentleman thief Arsène Lupin, is stolen by an interdimensional crime syndicate known as the Ganglars. However, they receive opposition from two Super Sentai teams: the Lupinrangers, who aim to steal back the collection to live up their namesake's reputation and save those they have lost, and the Patrangers, who are tasked with upholding justice by retrieving the collection and taking down the Gangler.
Nikita is a drug-addicted juvenile delinquent who was accused of killing a police officer in cold blood during an attempted robbery of a pharmacy. She is later arrested and sentenced to death by lethal injection, upon which she was secretly drugged by the government, faking her death. Nikita is then "recruited" by a secret government organization and transformed into a highly skilled assassin who cannot be traced.
Near the end of the Vietnam War, a spy who was embedded in the South Vietnam army flees to the United States and takes up residence in a refugee community, where he continues to gather intelligence and report back to the Viet Cong.
Carl Hamilton has just returned to Sweden after many years of secret education in the US when Stockholm is shaken by a series of terrorist attacks. Hamilton is assigned to assist the Swedish intelligence service in their pursuit of the guilty, but at the same time works as a double agent.
Sydney Bristow, an agent who has been tricked to believe she is working for the U.S. government, is actually working for a criminal organization named the Alliance of Twelve. Upon learning this, Sydney becomes a double agent for the real CIA.
