Keyword Insanity

Noong taong 2035, atubiling nagboluntaryo si James Cole na hinatulan na ibalik sa nakaraan upang matuklasan ang pinagmulan ng isang nakamamatay na virus na pumawi sa halos lahat ng populasyon ng mundo at pinilit ang mga nakaligtas sa mga komunidad sa ilalim ng lupa. Ngunit nang maling ipinadala si Cole sa 1990 sa halip na 1996, siya ay naaresto at nakakulong sa isang mental hospital. Doon niya nakilala ang psychiatrist na si Dr. Kathryn Railly, at ang pasyenteng si Jeffrey Goines, ang anak ng isang sikat na eksperto sa virus, na maaaring may hawak ng susi sa misteryosong rogue group, ang Army of the 12 Monkeys, na naisip na responsable sa pagpapakawala ng nakamamatay na sakit.

Ruthless siblings Roderick and Madeline Usher have built Fortunato Pharmaceuticals into an empire of wealth, privilege and power. But past secrets come to light when the heirs to the Usher dynasty start dying at the hands of a mysterious woman from their youth.

After causing a major incident, police officer Daigo Agawa takes his wife and daughter to live in the remote mountain village of Kuge. It seems the perfect place to recover from the ordeal, despite the mysterious disappearance of a previous officer posted there. One day, the body of an old woman is found on the mountain. The Goto family says she was attacked by a bear, but Daigo notices a human bite mark. It soon becomes clear that not all is as it seems in the village.